Hyaluronic serums with clinically tested active ingredients
4-fold hyaluronic acid complex for deep, multi-layer treatment & hydration
Choose Your HYA 4 Serum by Skin Concern
Whether you’re dealing with aging signs, breakouts, redness, or pigmentation – there's a HYA 4 Serum formulated just for you.
View ALL HYA 4 Serums
Showing 1–12 of 21 results
-
-
-
-
55,00 € – 91,00 €
-
50,00 € – 77,00 €
-
-
23,00 € – 119,00 €
-
Customer Reviews
carousel title
from 357 reviewsOur Proven Skincare System: DUAL LIFT® Routine
A highly effective HYA 4 Serum is just the beginning. To protect your results and support long-term skin resilience, we recommend pairing it with the LIA C 6 Cream as part of the DUAL LIFT® System:

Step 1
Apply after cleansing on slightly damp skin. It hydrates the dermis and delivers powerful actives deep where they’re most needed.

Step 2
Follow with a LIA C 6 Cream to protect the epidermis. It locks in hydration, strengthens the lipid barrier, and shields against photoaging. This two-step system treats both skin layers individually – far more effectively than “all-in-one” creams.
Targeted Solutions That Work Deep Within Your Skin
HYA 4 Serums – Active Ingredient Delivery for Visible Results
Looking for more than just hydration? Want a solution that targets specific skin concerns like blemishes, redness, or loss of firmness – right where the problem begins, deep in the skin?
Explore the HYA 4 Hyaluronic Serum collection from Dr. E. Voss. These serums combine high-performance active ingredients with advanced 4-tier hyaluronic acid technology. Think of it as a “delivery system” for your skin: Hyaluronic molecules act like a smart taxi, transporting actives precisely into the deeper skin layers – far beyond basic moisture care.
The Science Behind the HYA 4 Technology
How Our Hyaluronic Delivery System Transforms Skin
Each HYA 4 serum is a high-tech formula built on four molecular sizes of hyaluronic acid, carefully designed to reach and benefit every layer of your skin – from surface to deep dermis. The result? Skin that feels plumper, stronger, and more youthful from within.
Why 4 Types of Hyaluronic Acid?
Your skin isn’t one-dimensional. That’s why we use four precisely targeted hyaluronic types – each with a unique role in hydration and skin repair:

Long-chain (high molecular)
Acts as a breathable moisture veil. Locks in hydration and protects against external aggressors.
Macro-hyaluronic acid
Transports the active ingredients and strengthens the skin barrier from within. Calms redness and improves resilience.
Medium-size molecules
Penetrates deeper to create lasting hydration reservoirs. Also works as a carrier for actives.
Low molecular weight
Reaches the dermis, stimulates collagen, smooths wrinkles, and visibly firms the skin over time.
Frequently Asked Questions (FAQ)
What makes our serums special? A powerful combination of two key factors.
- Targeted Actives:
Each serum contains high concentrations of clinically tested ingredients, carefully selected to address a specific skin concern such as wrinkles, blemishes, or redness. We follow a synergistic approach: multiple active ingredients work together in each formula, with each one targeting a different aspect of the overall issue. This allows us to treat complex skin concerns more effectively and more gently at the same time.
Example – acne treatment: We address multiple contributing factors like hormonal imbalance, excess sebum production, impaired cell shedding, microbiome disruption, and inflammation – all in one formula that’s also suitable for sensitive skin. - Smart Delivery:
Our four-level hyaluronic acid technology not only delivers superior hydration but also acts as a “delivery taxi” for the active ingredients – especially thanks to its smallest molecular forms. These penetrate deep into the skin to unleash the full potential of the actives right where they’re needed. That’s the difference between surface-level care and truly effective problem-solving.
Why is the DUAL LIFT® system (serum + cream) so important?
The serum delivers moisture and actives into the dermis. But without sealing the skin with a lipid-rich cream, moisture escapes and the skin barrier weakens.
The LIA C 6 Cream seals in hydration, protects against external damage, and prevents premature aging. Think layered care – not one-size-fits-all.
How do I choose the right HYA 4 Serum?
Choose based on your current skin condition, not your skin type:
- Oily, blemish-prone skin → AKNEX or BIO CLEAR
- Wrinkles & loss of firmness → DEEP LIFT Q10 or EterCell
- Redness, sensitive skin → CAPIMED
- Tired eyes, dark circles → BRIGHT EYES
Are the serums suitable for sensitive skin?
Yes. All HYA 4 Serums are free from emulsifiers, fragrances, dyes, silicones, and parabens. Minimalist formulas, maximum effect – even for hypersensitive skin.
When will I see results?
You’ll notice a smoother, more hydrated feel immediately. For visible improvements (fewer blemishes, less redness, firmer skin), we recommend regular use for:
- 2–4 weeks for clarity and calm
- 2–3 months for wrinkle reduction
Since your skin’s natural hyaluronic levels decline with age, consistent daily use is key to maintaining healthy, plump skin.